Memory Efficient Minimum Substring Partitioning
Summary: Disk-based Minimum Substring Partitioning (MSP) enables memory-efficient de Bruijn graph construction for large genomes. Partitions reads into small in-memory chunks, processes them independently, and merges using k-mer overlaps to compress from Theta(kn) to Theta(n), enabling assembly on commodity hardware. (summarized by gpt-5-nano on Feb 09 2026)
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Authors
- 1. Yang Li (University of California Santa Barbara)
- 2. Pegah Kamousi (University of California Santa Barbara)
- 3. Fangqiu Han (University of California Santa Barbara)
- 4. Shengqi Yang (University of California Santa Barbara)
- 5. Xifeng Yan (University of California Santa Barbara)
- 6. Subhash Suri (University of California Santa Barbara)
BibTeX Citation
@article{li_vldb13,
title = {{Memory Efficient Minimum Substring Partitioning}},
author = {Li, Yang and Kamousi, Pegah and Han, Fangqiu and Yang, Shengqi and Yan, Xifeng and Suri, Subhash},
journal = {PVLDB},
series = {{VLDB} '13},
volume = {6},
number = {3},
pages = {169},
doi = {10.14778/2535569.2448951},
url = {https://doi.org/10.14778/2535569.2448951},
year = {2013}
}
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